Combinatorial strategies based on CRAd-IL24 and CRAd-ING4 virotherapy with anti-angiogenesis treatment for ovarian cancer

BACKGROUND: A major hurdle incurrent to the human clinical application of conditionally replicative adenovirus (CRAd)-based virotherapy agents is their limited therapeutic efficacy. In this study we evaluated whether arming our previously reported Ad5/3Δ24 CRAd vector containing a 24-base pair delet...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Ovarian Res
Auteurs principaux: Ashshi, Ahmad Mohammad, El-Shemi, Adel Galal, Dmitriev, Igor P., Kashentseva, Elena A., Curiel, David T.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924320/
https://ncbi.nlm.nih.gov/pubmed/27349517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-016-0248-5
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