IGF1R signalling in testicular germ cell tumour cells impacts on cell survival and acquired cisplatin resistance

Testicular germ cell tumours (TGCTs) are the most frequent malignancy and cause of death from solid tumours in the 20‐ to 40‐year age group. Although most cases show sensitivity to cis‐platinum‐based chemotherapy, this is associated with long‐term toxicities and chemo‐resistance. Roles for receptor...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Selfe, Joanna, Goddard, Neil C, McIntyre, Alan, Taylor, Kathryn R, Renshaw, Jane, Popov, Sergey D, Thway, Khin, Summersgill, Brenda, Huddart, Robert A, Gilbert, Duncan C, Shipley, Janet M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2018
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817239/
https://ncbi.nlm.nih.gov/pubmed/29160922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5008
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