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Synthesis of novel (−)-epicatechin derivatives as potential endothelial GPER agonists: evaluation of biological effects

To potentially identify proteins that interact (i.e. bind) and may contribute to mediate (−)-epicatechin (Epi) responses in endothelial cells we implemented the following strategy: 1) synthesis of novel Epi derivatives amenable to affinity column use, 2) in silico molecular docking studies of the no...

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Dettagli Bibliografici
Pubblicato in:Bioorg Med Chem Lett
Autori principali: Sarmiento, Viviana, Ramirez-Sanchez, Israel, Moreno-Ulloa, Aldo, Romero-Perez, Diego, Chávez, Daniel, Ortiz, Miguel, Najera, Nayelli, Correa-Basurto, Jose, Villarreal, Francisco, Ceballos, Guillermo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817025/
https://ncbi.nlm.nih.gov/pubmed/29395974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.01.025
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