Comparison of the effect of allopurinol and febuxostat on urinary 2,8-dihydroxyadenine excretion in patients with APRT deficiency: a clinical trial

INTRODUCTION: Adenine phosphoribosyltransferase deficiency (APRTd) is a rare, but significant, cause of kidney stones and progressive chronic kidney disease. The optimal treatment has not been established. The purpose of this pilot study was to compare the effect of the xanthine oxidoreductase inhib...

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Publicado no:Eur J Intern Med
Main Authors: Edvardsson, Vidar O, Runolfsdottir, Hrafnhildur L, Thorsteinsdottir, Unnur A, Agustsdottir, Inger M Sch, Oddsdottir, G Steinunn, Eiriksson, Finnur, Goldfarb, David S, Thorsteinsdottir, Margret, Palsson, Runolfur
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817015/
https://ncbi.nlm.nih.gov/pubmed/29241594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejim.2017.10.007
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