Therapeutic Effects of FGF23 c-tail Fc in a murine pre-clinical model of X-linked hypophosphatemia via the selective modulation of phosphate reabsorption

Fibroblast growth factor 23 (FGF23) is the causative factor of X-linked hypophosphatemia (XLH), a genetic disorder effecting 1:20,000 that is characterized by excessive phosphate excretion, elevated FGF23 levels and a rickets/osteomalacia phenotype. FGF23 inhibits phosphate reabsorption and suppress...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Bone Miner Res
Main Authors: Johnson, Kristen, Levine, Kymberly, Sergi, Joseph, Chamoun, Jean, Roach, Rachel, Vekich, Jackie, Favis, Mike, Horn, Mark, Cao, Xianjun, Miller, Brian, Snyder, William, Aivazian, Dikran, Reagan, William, Berryman, Edwin, Colangelo, Jennifer, Markiewicz, Victoria, Bagi, Cedo, Brown, Thomas P., Coyle, Anthony, Mohammadi, Moosa, Magram, Jeanne
פורמט: Artigo
שפה:Inglês
יצא לאור: 2017
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5816679/
https://ncbi.nlm.nih.gov/pubmed/28600887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3197
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