Polymerase delta-interacting protein 2 deficiency protects against blood-brain barrier permeability in the ischemic brain

BACKGROUND: Polymerase δ-interacting protein 2 (Poldip2) is a multifunctional protein that regulates vascular extracellular matrix composition and matrix metalloproteinase (MMP) activity. The blood-brain barrier (BBB) is a dynamic system assembled by endothelial cells, basal lamina, and perivascular...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Hernandes, Marina S., Lassègue, Bernard, Hilenski, Lula L., Adams, Jonathan, Gao, Ning, Kuan, Chia-Yi, Sun, Yu-Yo, Cheng, Lihong, Kikuchi, Daniel S., Yepes, Manuel, Griendling, Kathy K.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5816395/
https://ncbi.nlm.nih.gov/pubmed/29452577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-1032-1
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