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Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy

BACKGROUND: Sepsis-associated encephalopathy (SAE), a diffuse cerebral dysfunction in the absence of direct CNS infection, is associated with increased rates of mortality and morbidity in patients with sepsis. Increased cytokine production and disruption of the blood-brain barrier (BBB) are implicat...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Kikuchi, Daniel S., Campos, Ana Carolina P., Qu, Hongyan, Forrester, Steven J., Pagano, Rosana L., Lassègue, Bernard, Sadikot, Ruxana T., Griendling, Kathy K., Hernandes, Marina S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883676/
https://ncbi.nlm.nih.gov/pubmed/31779628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1575-4
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