Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib

PURPOSE: Vandetanib is well-tolerated in patients with advanced medullary thyroid carcinoma (MTC). Long-term outcomes and mechanisms of MTC progression have not been reported previously. DESIGN: We monitored toxicities and disease status in patients taking vandetanib for hereditary, advanced MTC. Tu...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Kraft, Ira L, Akshintala, Srivandana, Zhu, Yuelin, Lei, Haiyan, Derse-Anthony, Claudia, Dombi, Eva, Steinberg, Seth M, Lodish, Maya, Waguespack, Steven G, Kapustina, Oxana, Fox, Elizabeth, Balis, Frank M, Merino, Maria J, Meltzer, Paul S, Glod, John W, Shern, Jack F, Widemann, Brigitte C
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815946/
https://ncbi.nlm.nih.gov/pubmed/29187393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2101
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