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Patterns of thyroid hormone levels in pediatric medullary thyroid carcinoma patients on vandetanib therapy

BACKGROUND: Tyrosine kinase inhibitors (TKIs) have been associated with elevated TSH as a drug class effect. Prior studies of vandetanib in adults with medullary thyroid carcinoma (MTC) described an increase in levothyroxine (LT) requirement. We studied TSH, free T4, and LT dosing in children and ad...

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Bibliografische gegevens
Gepubliceerd in:Int J Pediatr Endocrinol
Hoofdauteurs: Lodish, Maya, Gkourogianni, Alexandra, Bornstein, Ethan, Sinaii, Ninet, Fox, Elizabeth, Chuk, Meredith, Marcus, Leigh, Akshintala, Srivandana, Balis, Frank, Widemann, Brigitte, Stratakis, Constantine A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429462/
https://ncbi.nlm.nih.gov/pubmed/25972901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1687-9856-2015-3
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