Merkel cell carcinoma patients presenting without a primary lesion have elevated markers of immunity, higher tumor mutation burden and improved survival

PURPOSE: Patients presenting with nodal Merkel cell carcinoma without an identifiable (unknown) primary lesion (MCC-UP) are nearly twice as likely to survive compared to similarly staged patients with known primary lesions (MCC-KP). The basis of this previously reported finding is unclear. EXPERIMEN...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Vandeven, Natalie, Lewis, Christopher W., Makarov, Vladimir, Riaz, Nadeem, Paulson, Kelly G., Hippe, Daniel, Bestick, Amy, Doumani, Ryan, Marx, Tessa, Takagishi, Seesha, Chan, Timothy A., Choi, Jaehyuk, Nghiem, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815931/
https://ncbi.nlm.nih.gov/pubmed/29246939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1678
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