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Autophagy Is Required for Sortilin-Mediated Degradation of Apolipoprotein B100

RATIONALE: Genome-Wide Association Studies identified single nucleotide polymorphisms (SNPs) near the SORT1 locus strongly associated with decreased plasma low-density lipoprotein cholesterol (LDL-C) levels and protection from atherosclerotic cardiovascular disease and myocardial infarction. The min...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Amengual, Jaume, Guo, Liang, Strong, Alanna, Madrigal-Matute, Julio, Wang, Haizhen, Kaushik, Susmita, Brodsky, Jeffrey L., Rader, Daniel J., Cuervo, Ana Maria, Fisher, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815905/
https://ncbi.nlm.nih.gov/pubmed/29301854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.311240
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