Pannexin 1 Channels as an Unexpected New Target of the Anti-Hypertensive Drug Spironolactone

RATIONALE: Resistant hypertension is a major health concern with unknown etiology. Spironolactone is an effective anti-hypertensive drug, especially for patients with resistant hypertension, and is considered by the World Health Organization (WHO) as an “essential” medication. Although spironolacton...

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Veröffentlicht in:Circ Res
Hauptverfasser: Good, Miranda E., Chiu, Yu-Hsin, Poon, Ivan K. H., Medina, Chris, Butcher, Joshua T., Mendu, Suresh K., DeLalio, Leon J., Lohman, Alexander W., Leitinger, Norbert, Barrett, Eugene, Lorenz, Ulrike M., Desai, Bimal N., Jaffe, Iris Z., Bayliss, Douglas A., Isakson, Brant E., Ravichandran, Kodi S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815904/
https://ncbi.nlm.nih.gov/pubmed/29237722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.312380
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