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The choice of linker for conjugating R848 to inactivated influenza virus determines the stimulatory capacity for innate immune cells

Inactivated influenza vaccines are not approved for use in infants less than 6 months of age due to poor immunogenicity in that population. While the live attenuated influenza vaccine has the potential to be more immunogenic, it is not an option for infants and other vulnerable populations, includin...

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Publicado en:Vaccine
Main Authors: Westcott, Marlena M., Clemens, Elene A., Holbrook, Beth C., King, S. Bruce, Alexander-Miller, Martha A.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815857/
https://ncbi.nlm.nih.gov/pubmed/29398273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2018.01.035
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