An R848 adjuvanted influenza vaccine promotes early activation of B cells in the draining lymph nodes of non‐human primate neonates

Impaired immune responsiveness is a significant barrier to vaccination of neonates. By way of example, the low seroconversion observed following influenza vaccination has led to restriction of its use to infants over 6 months of age, leaving younger infants vulnerable to infection. Our previous stud...

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Vydáno v:Immunology
Hlavní autoři: Holbrook, Beth C., Aycock, S. Tyler, Machiele, Emily, Clemens, Elene, Gries, Danielle, Jorgensen, Matthew J., Hadimani, Mallinath B., King, S. Bruce, Alexander‐Miller, Martha A.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795180/
https://ncbi.nlm.nih.gov/pubmed/28940186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12845
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