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A highly malignant case of neuroblastoma with substantial increase of single-nucleotide variants and normal mismatch repair system: A case report

RATIONALE: Neuroblastoma is a common abdominal malignancy in children. The chemoresistant and relapsed cases have poor prognosis. The genetic background and the mechanism of resistance remain unelucidated. Next-generation sequence (NGS) is becoming a popular tool to unravel the genetic background an...

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Библиографические подробности
Опубликовано в: :Medicine (Baltimore)
Главные авторы: Yuan, Lin-Qing, Wang, Jin-Hu, Zhu, Kun, Yang, Min, Gu, Wei-Zhong, Lai, Can, Li, Hao-Min, Shu, Qiang, Chen, Xi
Формат: Artigo
Язык:Inglês
Опубликовано: Wolters Kluwer Health 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815686/
https://ncbi.nlm.nih.gov/pubmed/29390274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000008845
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