Axonal ribosomes and mRNAs associate with fragile X granules in adult rodent and human brains

Local mRNA translation in growing axons allows for rapid and precise regulation of protein expression in response to extrinsic stimuli. However, the role of local translation in mature CNS axons is unknown. Such a mechanism requires the presence of translational machinery and associated mRNAs in cir...

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Vydáno v:Hum Mol Genet
Hlavní autoři: Akins, Michael R., Berk-Rauch, Hanna E., Kwan, Kenneth Y., Mitchell, Molly E., Shepard, Katherine A., Korsak, Lulu I. T., Stackpole, Emily E., Warner-Schmidt, Jennifer L., Sestan, Nenad, Cameron, Heather A., Fallon, Justin R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815656/
https://ncbi.nlm.nih.gov/pubmed/28082376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw381
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