Axonal ribosomes and mRNAs associate with fragile X granules in adult rodent and human brains

Local mRNA translation in growing axons allows for rapid and precise regulation of protein expression in response to extrinsic stimuli. However, the role of local translation in mature CNS axons is unknown. Such a mechanism requires the presence of translational machinery and associated mRNAs in cir...

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Pubblicato in:Hum Mol Genet
Autori principali: Akins, Michael R., Berk-Rauch, Hanna E., Kwan, Kenneth Y., Mitchell, Molly E., Shepard, Katherine A., Korsak, Lulu I. T., Stackpole, Emily E., Warner-Schmidt, Jennifer L., Sestan, Nenad, Cameron, Heather A., Fallon, Justin R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815656/
https://ncbi.nlm.nih.gov/pubmed/28082376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw381
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