Association of an intact E2 gene with higher HPV viral load, higher viral oncogene expression, and improved clinical outcome in HPV16 positive head and neck squamous cell carcinoma

To assess the relationship of E2 gene disruption with viral gene expression and clinical outcome in human papillomavirus (HPV) positive head and neck squamous cell carcinoma, we evaluated 31 oropharyngeal and 17 non-oropharyngeal HPV16 positive carcinomas using two PCR-based methods to test for disr...

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Bibliographic Details
Published in:	PLoS One
Main Authors:	Anayannis, Nicole V., Schlecht, Nicolas F., Ben-Dayan, Miriam, Smith, Richard V., Belbin, Thomas J., Ow, Thomas J., Blakaj, Duk M., Burk, Robert D., Leonard, Sarah M., Woodman, Ciaran B., Parish, Joanna L., Prystowsky, Michael B.
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science 2018
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5815588/ https://ncbi.nlm.nih.gov/pubmed/29451891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191581
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Association of an intact E2 gene with higher HPV viral load, higher viral oncogene expression, and improved clinical outcome in HPV16 positive head and neck squamous cell carcinoma

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