The DNA Pol ε stimulatory activity of Mrc1 is modulated by phosphorylation

DNA replication checkpoint (Mec1-Mrc1-Rad53 in budding yeast) is an evolutionarily conserved surveillance system to ensure proper DNA replication and genome stability in all eukaryotes. Compared to its well-known function as a mediator of replication checkpoint, the exact role of Mrc1 as a component...

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Publicado no:Cell Cycle
Main Authors: Zhang, Zhong-Xin, Zhang, Jingjing, Cao, Qinhong, Campbell, Judith L., Lou, Huiqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815433/
https://ncbi.nlm.nih.gov/pubmed/29157061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1403680
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