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Transcriptional Regulation of Telomeric Expression Sites and Antigenic Variation in Trypanosomes

INTRODUCTION: Trypanosoma brucei uses antigenic variation to evade the host antibody clearance by periodically changing its Variant Surface Glycoprotein (VSGs) coat. T. brucei encode over 2,500 VSG genes and pseudogenes, however they transcribe only one VSG gene at time from one of the 20 telomeric...

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Detalhes bibliográficos
Publicado no:Curr Genomics
Main Authors: Cestari, Igor, Stuart, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814960/
https://ncbi.nlm.nih.gov/pubmed/29491740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1389202918666170911161831
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