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Nuclear mRNA degradation tunes the gain of the unfolded protein response in Saccharomyces cerevisiae

Unfolded protein response (UPR) is triggered by the accumulation of unfolded proteins in the endoplasmic reticulum (ER), which is accomplished by a dramatic induction of genes encoding ER chaperones. Activation of these genes involves their rapid transcription by Hac1p, encoded by the HAC1 precursor...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Sarkar, Debasish, Paira, Sunirmal, Das, Biswadip
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814838/
https://ncbi.nlm.nih.gov/pubmed/29165698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1160
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