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Nuclear mRNA degradation tunes the gain of the unfolded protein response in Saccharomyces cerevisiae

Unfolded protein response (UPR) is triggered by the accumulation of unfolded proteins in the endoplasmic reticulum (ER), which is accomplished by a dramatic induction of genes encoding ER chaperones. Activation of these genes involves their rapid transcription by Hac1p, encoded by the HAC1 precursor...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Sarkar, Debasish, Paira, Sunirmal, Das, Biswadip
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814838/
https://ncbi.nlm.nih.gov/pubmed/29165698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1160
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