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Insights into the structural and mechanistic basis of multifunctional S. cerevisiae Pif1p helicase
The Saccharomyces cerevisiae Pif1 protein (ScPif1p) is the prototypical member of the Pif1 family of DNA helicases. ScPif1p is involved in the maintenance of mitochondrial, ribosomal and telomeric DNA and suppresses genome instability at G-quadruplex motifs. Here, we report the crystal structures of...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5814829/ https://ncbi.nlm.nih.gov/pubmed/29202194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1217 |
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