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Insights into the structural and mechanistic basis of multifunctional S. cerevisiae Pif1p helicase

The Saccharomyces cerevisiae Pif1 protein (ScPif1p) is the prototypical member of the Pif1 family of DNA helicases. ScPif1p is involved in the maintenance of mitochondrial, ribosomal and telomeric DNA and suppresses genome instability at G-quadruplex motifs. Here, we report the crystal structures of...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Lu, Ke-Yu, Chen, Wei-Fei, Rety, Stephane, Liu, Na-Nv, Wu, Wen-Qiang, Dai, Yang-Xue, Li, Dan, Ma, Hai-Yun, Dou, Shuo-Xing, Xi, Xu-Guang
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814829/
https://ncbi.nlm.nih.gov/pubmed/29202194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1217
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