Hypoxia promotes primitive glycosaminoglycan-rich extracellular matrix composition in developing heart valves

During postnatal heart valve development, glycosaminoglycan (GAG)-rich valve primordia transform into stratified valve leaflets composed of GAGs, fibrillar collagen, and elastin layers accompanied by decreased cell proliferation as well as thinning and elongation. The neonatal period is characterize...

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Dades bibliogràfiques
Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Amofa, Dorothy, Hulin, Alexia, Nakada, Yuji, Sadek, Hesham A., Yutzey, Katherine E.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814654/
https://ncbi.nlm.nih.gov/pubmed/28842437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00209.2017
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