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USP35 regulates mitotic progression by modulating the stability of Aurora B

Although approximately 100 deubiquitinating enzymes (DUBs) are encoded in the human genome, very little is known about the DUBs that function in mitosis. Here, we demonstrate that DUB USP35 functions as a mitotic regulator by controlling the protein levels and downstream signaling of Aurora B and th...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Park, Jinyoung, Kwon, Mi-Sun, Kim, Eunice EunKyeong, Lee, Hyunsook, Song, Eun Joo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814453/
https://ncbi.nlm.nih.gov/pubmed/29449677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03107-0
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