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Intravenous synthetic platelet (SynthoPlate) nanoconstructs reduce bleeding and improve ‘golden hour’ survival in a porcine model of traumatic arterial hemorrhage

Traumatic non-compressible hemorrhage is a leading cause of civilian and military mortality and its treatment requires massive transfusion of blood components, especially platelets. However, in austere civilian and battlefield locations, access to platelets is highly challenging due to limited suppl...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hickman, DaShawn A., Pawlowski, Christa L., Shevitz, Andrew, Luc, Norman F., Kim, Ann, Girish, Aditya, Marks, Joyann, Ganjoo, Simi, Huang, Stephanie, Niedoba, Edward, Sekhon, Ujjal D. S., Sun, Michael, Dyer, Mitchell, Neal, Matthew D., Kashyap, Vikram S., Sen Gupta, Anirban
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814434/
https://ncbi.nlm.nih.gov/pubmed/29449604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21384-z
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