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A factor VIII-derived peptide enables von Willebrand factor (VWF)-binding of artificial platelet nanoconstructs without interfering with VWF-adhesion of natural platelets

There is substantial clinical interest in synthetic platelet analogs for potential application in transfusion medicine. To this end, our research is focused on self-assembled peptide–lipid nanoconstructs that can undergo injury site-selective adhesion and subsequently promote site-directed active pl...

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Detalhes bibliográficos
Publicado no:Nanoscale
Main Authors: Haji-Valizadeh, Hassa n, Modery-Pawlowski, Christa L., Sen Gupta, Anirban
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300948/
https://ncbi.nlm.nih.gov/pubmed/24658160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3nr06400j
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