Lysine-specific demethylase 1 inhibitors prevent teratoma development from human induced pluripotent stem cells

Human induced pluripotent stem cells (hiPSCs) are creating great expectations for regenerative medicine. However, safety strategies must be put in place to guard against teratoma formation after transplantation of hiPSC-derived cells into patients. Recent studies indicate that epigenetic regulators...

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Udgivet i:Oncotarget
Main Authors: Osada, Naoki, Kikuchi, Jiro, Umehara, Takashi, Sato, Shin, Urabe, Masashi, Abe, Tomoyuki, Hayashi, Nakanobu, Sugitani, Masahiko, Hanazono, Yutaka, Furukawa, Yusuke
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814224/
https://ncbi.nlm.nih.gov/pubmed/29464084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24030
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