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Combining molecular and immunohistochemical analyses of key drivers in primary melanomas: interplay between germline and somatic variations

Due to the high mutational somatic burden of Cutaneous Malignant Melanoma (CMM) a thorough profiling of the driver mutations and their interplay is necessary to explain the timing of tumorigenesis or for the identification of actionable genetic events. The aim of this study was to establish the muta...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Bruno, William, Martinuzzi, Claudia, Dalmasso, Bruna, Andreotti, Virginia, Pastorino, Lorenza, Cabiddu, Francesco, Gualco, Marina, Spagnolo, Francesco, Ballestrero, Alberto, Queirolo, Paola, Grillo, Federica, Mastracci, Luca, Ghiorzo, Paola
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814167/
https://ncbi.nlm.nih.gov/pubmed/29464027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23204
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