Timed sequential therapy for acute myelogenous leukemia: Results of a retrospective study of 301 patients and review of the literature

Timed sequential therapy (TST) aims to improve outcomes in acute myelogenous leukemia (AML) by harnessing drug-induced cell cycle kinetics of AML, where a second drug is timed to coincide with peak leukemia proliferation induced by the first drugs. We analyzed outcomes in 301 newly diagnosed AML pat...

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Veröffentlicht in:Leuk Res
Hauptverfasser: Norsworthy, Kelly J., DeZern, Amy E., Tsai, Hua-Ling, Hand, Wesley A., Varadhan, Ravi, Gore, Steven D., Gojo, Ivana, Pratz, Keith, Carraway, Hetty E., Showel, Margaret, McDevitt, Michael A., Gladstone, Douglas, Ghiaur, Gabriel, Prince, Gabrielle, Seung, Amy H., Benani, Dina, Levis, Mark J., Karp, Judith E., Smith, B. Douglas
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813685/
https://ncbi.nlm.nih.gov/pubmed/28869816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2017.08.009
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