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1.14*CM1A-LBCC: Localized Bond Charge Corrected CM1A Charges for Condensed-Phase Simulations

The quality of the 1.14*CM1A and 1.20*CM5 charge models was evaluated for calculations of free energies of hydration. For a set of 426 neutral molecules, 1.14*CM1A and 1.20*CM5 yield MADs of 1.26 and 1.20 kcal/mol, respectively. The 1.14*CM1A charges, which can be readily obtained for large systems,...

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Publicat a:J Phys Chem B
Autors principals: Dodda, Leela S., Vilseck, Jonah Z., Tirado-Rives, Julian, Jorgensen, William L.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813481/
https://ncbi.nlm.nih.gov/pubmed/28224794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b00272
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