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Evaluation of reaction gap-filling accuracy by randomization

BACKGROUND: Completion of genome-scale flux-balance models using computational reaction gap-filling is a widely used approach, but its accuracy is not well known. RESULTS: We report on computational experiments of reaction gap filling in which we generated degraded versions of the EcoCyc-20.0-GEM mo...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Latendresse, Mario, Karp, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813426/
https://ncbi.nlm.nih.gov/pubmed/29444634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2050-4
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