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Hypoxia-induced the upregulation of stromal cell-derived factor 1 in fibroblast-like synoviocytes contributes to migration of monocytes into synovium tissue in rheumatoid arthritis

BACKGROUND: Rheumatoid arthritis (RA) is an auto-immune disease characterized by chronic inflammation of multiple joints. Hypoxia is a constant feature of synovial microenvironment in RA. Fibroblast-like synoviocytes (FLSs), which are potent effector cells in RA. It has been reported that large numb...

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Bibliografski detalji
Izdano u:Cell Biosci
Glavni autori: Yang, Ru, Yao, Yanhua, Wang, Panjun
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813381/
https://ncbi.nlm.nih.gov/pubmed/29456830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-018-0210-x
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