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ERAD‐dependent control of the Wnt secretory factor Evi

Active regulation of protein abundance is an essential strategy to modulate cellular signaling pathways. Within the Wnt signaling cascade, regulated degradation of β‐catenin by the ubiquitin‐proteasome system (UPS) affects the outcome of canonical Wnt signaling. Here, we found that abundance of the...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Glaeser, Kathrin, Urban, Manuela, Fenech, Emma, Voloshanenko, Oksana, Kranz, Dominique, Lari, Federica, Christianson, John C, Boutros, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813261/
https://ncbi.nlm.nih.gov/pubmed/29378775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797311
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