Pharmacokinetic-pharmacodynamic correlations in the development of ginger extract as an anticancer agent

Anticancer efficacy of ginger phenolics (GPs) has been demonstrated in various in vitro assays and xenograft mouse models. However, only sub-therapeutic plasma concentrations of GPs were detected in human and mouse pharmacokinetic (PK) studies. Intriguingly, a significant portion of GPs occurred as...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Mukkavilli, Rao, Yang, Chunhua, Tanwar, Reenu Singh, Saxena, Roopali, Gundala, Sushma R., Zhang, Yingyi, Ghareeb, Ahmed, Floyd, Stephan D., Vangala, Subrahmanyam, Kuo, Wei-Wen, Rida, Padmashree C. G., Aneja, Ritu
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813242/
https://ncbi.nlm.nih.gov/pubmed/29445099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21125-2
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares