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Expression of the FGFR2c mesenchymal splicing variant in human keratinocytes inhibits differentiation and promotes invasion

The altered isoform switching of the fibroblast growth factor receptor 2 (FGFR2) and aberrant expression of the mesenchymal FGFR2c isoform in epithelial cells is involved in cancer progression. We have recently described that the ectopic expression of FGFR2c in normal human keratinocytes induces epi...

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Publicat a:Mol Carcinog
Autors principals: Ranieri, Danilo, Rosato, Benedetta, Nanni, Monica, Belleudi, Francesca, Torrisi, Maria Rosaria
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813158/
https://ncbi.nlm.nih.gov/pubmed/29068468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22754
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