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Mutations in the West Nile prM protein affect VLP and virion secretion in vitro
Mutation of the West Nile virus-like particle (WN VLP) prM protein (T20D, K31A, K31V, or K31T) results in undetectable VLP secretion from transformed COS-1 cells. K31 mutants formed intracellular prM-E heterodimers; however these proteins remained in the ER and ER–Golgi intermediary compartments of...
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| Veröffentlicht in: | Virology |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5812725/ https://ncbi.nlm.nih.gov/pubmed/22858174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.07.011 |
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