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NF-κB-Chromatin Interactions Drive Diverse Phenotypes by Modulating Transcriptional Noise

Noisy gene expression generates diverse phenotypes, but little is known about mechanisms that modulate noise. Combining experiments and modeling, we studied how tumor necrosis factor (TNF) initiates noisy expression of latent HIV via the transcription factor nuclear factor κB (NF-κB) and how the HIV...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Wong, Victor C., Bass, Victor L., Bullock, M. Elise, Chavali, Arvind K., Lee, Robin E.C., Mothes, Walther, Gaudet, Suzanne, Miller-Jensen, Kathryn
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812697/
https://ncbi.nlm.nih.gov/pubmed/29346759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.12.080
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