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Antitumor effects of metformin via indirect inhibition of protein phosphatase 2A in patients with endometrial cancer
OBJECTIVE: Metformin, an antidiabetic drug, inhibits the endometrial cancer cell growth in vivo by improving the insulin resistance; however, its mechanism of action is not completely understood. Protein phosphatase 2A (PP2A) is a serine/threonine phosphatase associated with insulin resistance and t...
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| I publikationen: | PLoS One |
|---|---|
| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Public Library of Science
2018
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5812621/ https://ncbi.nlm.nih.gov/pubmed/29444159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192759 |
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