LY2405319, an analog of fibroblast growth factor 21 ameliorates α-smooth muscle actin production through inhibition of the succinate—G-protein couple receptor 91 (GPR91) pathway in mice

Fibroblast growth factor 21 (FGF21) is an important metabolic regulator expressed predominantly in the liver. In this study, we evaluated the role of LY2405319, an analogue of FGF21, in hepatic stellate cell (HSC) activation and in a methionine and choline-deficient (MCD)-diet induced mouse model of...

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Udgivet i:PLoS One
Main Authors: Le, Cong Thuc, Nguyen, Giang, Park, So Young, Choi, Dae Hee, Cho, Eun-Hee
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812602/
https://ncbi.nlm.nih.gov/pubmed/29444136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192146
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