The Succinate Receptor GPR91 Is Involved in Pressure Overload-Induced Ventricular Hypertrophy

BACKGROUND: Pulmonary arterial hypertension is characterized by increased pressure overload that leads to right ventricular hypertrophy (RVH). GPR91 is a formerly orphan G-protein-coupled receptor (GPCR) that has been characterized as a receptor for succinate; however, its role in RVH remains unknow...

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Udgivet i:PLoS One
Main Authors: Yang, Lei, Yu, Di, Mo, Ran, Zhang, Jiru, Hua, Hu, Hu, Liang, Feng, Yu, Wang, Song, Zhang, Wei-yan, Yin, Ning, Mo, Xu-Ming
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732750/
https://ncbi.nlm.nih.gov/pubmed/26824665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147597
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