Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumours

The mammary gland is composed of a complex cellular hierarchy with unusual postnatal plasticity. The identities of stem/progenitor cell populations, as well as tumour-initiating cells that give rise to breast cancer, are incompletely understood. Here we show that Lgr6 marks rare populations of cells...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Blaas, Leander, Pucci, Fabio, Messal, Hendrik A., Andersson, Agneta B., Ruiz, E. Josue, Gerling, Marco, Douagi, Iyadh, Spencer-Dene, Bradley, Musch, Alexandra, Mitter, Richard, Bhaw, Leena, Stone, Richard, Bornhorst, Dorothee, Sesay, Abdul K., Jonkers, Jos, Stamp, Gordon, Malanchi, Ilaria, Toftgård, Rune, Behrens, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812439/
https://ncbi.nlm.nih.gov/pubmed/27798604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3434
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