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Alterations in Cancer Stem Cell Marker CD44 Expression Predict Oncologic Outcome in Soft Tissue Sarcomas

BACKGROUND: Cancer stem cells (CSCs) have been shown to resist chemotherapy and promote metastasis after cytotoxic therapies. We sought to determine if the expression of CSC markers (ALDH, CD44, and EGFR) predicted outcomes in soft tissue sarcoma (STS) patients. METHODS: We queried an institutional...

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Bibliografiske detaljer
Udgivet i:J Surg Res
Main Authors: Henderson, Timothy, Chen, Mingyi, Darrow, Morgan A., Li, Chin-Shang, Chiu, Chi-Lu, Monjazeb, Arta M., Murphy, William J., Canter, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812363/
https://ncbi.nlm.nih.gov/pubmed/29433875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2017.11.016
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