A novel miR-375-HOXB3-CDCA3/DNMT3B regulatory circuitry contributes to leukemogenesis in acute myeloid leukemia

BACKGROUND: Acute myeloid leukemia (AML) is a heterogeneous group of hematopoietic malignancies due to sophisticated genetic mutations and epigenetic dysregulation. MicroRNAs (miRNAs), a class of small non-coding RNAs, are important regulators of gene expression in all biological processes, includin...

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Vydáno v:BMC Cancer
Hlavní autoři: Bi, Laixi, Zhou, Bin, Li, Haiying, He, Licai, Wang, Chunjing, Wang, Zhonggai, Zhu, Liqing, Chen, Mengqian, Gao, Shenmeng
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811974/
https://ncbi.nlm.nih.gov/pubmed/29439669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4097-z
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