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Model‐Based Approach to Predict Adherence to Protocol During Antiobesity Trials

Development of antiobesity drugs is continuously challenged by high dropout rates during clinical trials. The objective was to develop a population pharmacodynamic model that describes the temporal changes in body weight, considering disease progression, lifestyle intervention, and drug effects. Mar...

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Detalhes bibliográficos
Publicado no:J Clin Pharmacol
Main Authors: Sharma, Vishnu D., Combes, François P., Vakilynejad, Majid, Lahu, Gezim, Lesko, Lawrence J., Trame, Mirjam N.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811797/
https://ncbi.nlm.nih.gov/pubmed/28858397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.994
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