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Application of pharmacometric approaches to evaluate effect of weight and renal function on pharmacokinetics of alogliptin
AIMS: The aims of the study were to characterize the pharmacokinetics (PK) of alogliptin in healthy and type 2 diabetes mellitus (T2DM) subjects using a population PK approach and to assess the influence of various covariates on alogliptin exposure. METHODS: Plasma concentration data collected from...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4799927/ https://ncbi.nlm.nih.gov/pubmed/26617339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12853 |
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