Structural properties of apolipoprotein A-I mimetic peptides that promote ABCA1-dependent cholesterol efflux

Peptides mimicking the major protein of highdensity lipoprotein (HDL), apolipoprotein A-I (apoA-I), are promising therapeutics for cardiovascular diseases. Similar to apoA-I, their atheroprotective property is attributed to their ability to form discoidal HDL-like particles by extracting cellular ch...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Islam, Rafique M., Pourmousa, Mohsen, Sviridov, Denis, Gordon, Scott M., Neufeld, Edward B., Freeman, Lita A., Perrin, B. Scott, Pastor, Richard W., Remaley, Alan T.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811490/
https://ncbi.nlm.nih.gov/pubmed/29440748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20965-2
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