5A Apolipoprotein Mimetic Peptide Promotes Cholesterol Efflux and Reduces Atherosclerosis in Mice

Intravenous administration of apolipoprotein (apo) A-I complexed with phospholipid has been shown to rapidly reduce plaque size in both animal models and humans. Short synthetic amphipathic peptides can mimic the antiatherogenic properties of apoA-I and have been proposed as alternative therapeutic...

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Détails bibliographiques
Auteurs principaux: Amar, Marcelo J. A., D'Souza, Wilissa, Turner, Scott, Demosky, Stephen, Sviridov, Denis, Stonik, John, Luchoomun, Jayraz, Voogt, Jason, Hellerstein, Marc, Sviridov, Dmitri, Remaley, Alan T.
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2010
Sujets:
Cardiovascular
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913774/
https://ncbi.nlm.nih.gov/pubmed/20484557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.167890
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