An Apolipoprotein A-I Mimetic Peptide Designed with a Reductionist Approach Stimulates Reverse Cholesterol Transport and Reduces Atherosclerosis in Mice

Apolipoprotein A-I (apoA-I) mimetic peptides are considered a promising novel therapeutic approach to prevent and/or treat atherosclerosis. An apoA-I mimetic peptide ELK-2A2K2E was designed with a reductionist approach and has shown exceptional activity in supporting cholesterol efflux but modest an...

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Detalhes bibliográficos
Main Authors: Ditiatkovski, Michael, D’Souza, Wilissa, Kesani, Rajitha, Chin-Dusting, Jaye, de Haan, Judy B., Remaley, Alan, Sviridov, Dmitri
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706315/
https://ncbi.nlm.nih.gov/pubmed/23874769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068802
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