Type 2 Innate Lymphocytes Actuate Immunity Against Tumours and Limit Cancer Metastasis

Type 2 innate lymphoid cells (ILC2) potentiate immune responses, however, their role in mediating adaptive immunity in cancer has not been assessed. Here, we report that mice genetically lacking ILC2s have significantly increased tumour growth rates and conspicuously higher frequency of circulating...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Saranchova, Iryna, Han, Jeffrey, Zaman, Rysa, Arora, Hitesh, Huang, Hui, Fenninger, Franz, Choi, Kyung Bok, Munro, Lonna, Pfeifer, Cheryl G., Welch, Ian, Takei, Fumio, Jefferies, Wilfred A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811448/
https://ncbi.nlm.nih.gov/pubmed/29440650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20608-6
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